Peggy Noonan, who is often quite unimpressive in my view, gets one right in this blog post.
In previous IRS scandals it was the powerful abusing the powerful—a White House moving against prominent financial or journalistic figures who, because of their own particular status or the machineries at their disposal, could pretty much take care of themselves. A scandal erupts, there are headlines, and then people go on their way. The dreadful thing about this scandal, what makes it ominous, is that this is the elites versus regular citizens. It’s the mighty versus normal people. It’s the all-powerful directors of the administrative state training their eyes and moving on uppity and relatively undefended Americans.
That’s what makes this scandal different, and why if it’s not stopped now it will never stop. Because every four years you can get yourself a new president and a new White House, but you won’t easily get yourself a whole new administrative state. It’s there, it’s not going away, not anytime soon. If it isn’t forced back into its cage now, and definitively, it will prowl the land hungrily forever.
There's another thing that's different about this one. In this case we have an arm of the government going after private citizens on behalf of a political party — the Democrats.